Prof. Pamhidzai Dzomba

Qualifications

  • PhD: Physical Organic Chemistry, University of Zimbabwe
  • Masters of Analytical Chemistry, Bindura University
  • Bachelor of Science Education Honours in Chemistry, Bindura University
  • Diploma in Education (Physics, Chemistry, Biology),University of Zimbabwe


Mobile Number: +263 773 474 525
Email: pdzomba@gmail.com, pdzomba@buse.ac.zw

Research interests:

  • Traditional medicines and indigenous foods: Medico-nutritional properties and application to improve health and facilitate healing. Special interests are on diseases such as malaria, cholera, diabetes, obesity, cancers and hypertension.
  • Heavy metal toxicology in indigenous medicinal and food plants
  • Developing low cost and green household and laboratory chemicals
  • Drug discovery, efficacy studies and synthesis and impact of drugs on the environment.

Current research

  • Anti-obesity activity of dietary flavonoids
  • Antioxidant activity of phenolic compounds from indigenous food and medicinal plants
  • Development of bio-veterinary drugs for remediating diseases in poultry

Publications:

2021

  • Pamhidzai Dzomba and George Mhini (2020). Isolation and Quantification of Flavonoids from Kigelia africana (lam.) benth Fruit and Bark and their Antiradical and Antibacterial Activity. Tanzania Journal of Science 47(1): 57-69, 2021

2020

  • Pamhidzai Dzomba and Mark F Zaranyika (2020) Persistence and Fate of Chlortetracycline in the Aquatic Environment under sub-Tropical Conditions: Generation and Dissipation of Metabolites. Journal of Environmental Science and Health, Part B, DOI: 10.1080/03601234.2020.1854009
  • Pamhidzai Dzomba· Cleopas Mureya· Luke Gwatidzo (2020). Nematicidal Activity of phytocompounds from Piliostigma thonningii Stem Bark against Meloidogyne javanica. Chemistry Africa, https://doi.org/10.1007/s42250-020-00158-z
  • Pamhidzai Dzomba and Chidavayenzi Tinevimbo (2020) Effects of 15 Local Medicinal Plant Species on Protein Tyrosine Phosphatase 1B and Dipeptidyl Peptidase 1V Activity as Herbal Antidiabetic Type 2 Remedies.Tanzania Journal of Science 46(2): 317-328
  • Muchuweni E, Sathiaraj TS, Magama M.T, Dzomba P. (2020).  Effect of annealing on the optical constants of ZnO nanowires for energy harvesting applications. Journal of Optoelectronics and Advanced Materials, 22, No. 3-4: 200 – 204
  • Masimba Tapera, Ruth Wanjau, Pamhidzai Dzomba, Alex K. Machocho, Jane Mburu (2020). Phytochemical study to validate the ethnobotanical importance of Dioscorea steriscus tubers obtained from Zimbabwe, STED Journal. 2(1). May 2020
  • Masimba Tapera, Ruth Wanjau, Alex K. Machocho and Pamhidzai Dzomba (2020) Use of Polyphenol Extracts from Dioscorea steriscus and Plecranthus esculentus N.E.Br Tubers to Curb Oxidative Deterioration of Sunflower Oil. South Asian Research Journal of Natural Products 3(1): 18-28, 2020; Article no.SARJNP.55089

2019

  • H. Rambwawasvika, P. Dzomba and L. Gwatidzo (2019). Hair Growth Promoting Effect of Dicerocaryum senecioides Phytochemicals, International Journal of Medicinal Chemistry, Volume 2019, Article ID 7105834, 10 pages, https://doi.org/10.1155/2019/7105834
  • Zaranyika MF, Dzomba P. (2019). Dissipation of chlortetracycline in the aquatic environment: characterization in terms of a generalized multiphase pseudo-zero-order rate law. Int J Chem Kinetic.;1-14. https://doi.org/10.1002/kin.21311
  • Pamhidzai Dzomba, Estele Mwanza. (2019) Dipeptidyl peptidase IV and ?-glucosidase inhibitory activity of four bush okra species; Ceratotheca sesamoides, Corchorus fascicularis, Corchorus olitorius and Abelmoschus esculentus in ethnobotanical diabetic T2 management, Journal of Applied Sciences. 19: 586-592

2018

  • Hardlife Rambwawasvika, Pamhidzai Dzomba and Luke Gwatidzo, (2018). In vitro Study of Phytochemical Composition and Antifungal Activity of Dicerocaryum senecioides Leaf Extract. Pharmacologia, 9: 137-143. DOI: 10.5567/pharmacologia.2018
  • Luke Gwatidzo, Pamhidzai Dzomba and Mkululi Mangena. TLC separation and antioxidant activity of flavonoids from Carissa bispinosa, Ficus sycomorus, and Grewia bicolar fruits. Nutrire (2018) 43:3. DOI 10.1186/s41110-018-0062-5

2017

  • Dzomba, P, Gwatidzo, L, Mugari, P. and Mupa, M. (2017). Traditional dishes consumed in Zimbabwe and high-performance liquid chromatography (HPLC) quantitation of their antioxidant phytochemicals, African Journal of Biotechnology, 16(26): 1461-1473

2016

  • Mupa M, Shereni K., Dzomba P (2016). Pennisetum purpureum Ash Silica Immobilized Sugarcane Bagasse Bio-Sorbent for Basic Dye Effluent Treatment. Research Journal of Chemical Environment Science.4 (3) 71-78

  • Dzomba P, L. Gwatidzo, K. Mtwazi, M. Mupa (2016).Screening and HPLC quantitation of phytocompounds with antiobesity activity in traditional teas consumed in Zimbabwe. Der Pharma Chemica, 8(18):255-265

2015

  • Mark F. Zaranyika, Pamhidzai Dzomba and Jameson Kugara (2015). Degradation of oxytetracycline in the aquatic environment: a proposed steady state kinetic model that takes into account hydrolysis, photolysis, microbial degradation and adsorption by colloidal and sediment particles. Environmental chemistry; Csiro publishing 12 (2): 174-188; http://dx.doi.org/10.1071/EN14116.
  • M. F. Zaranyika, P. Dzomba, J. Kugara (2015). Speciation and persistence of doxycycline in the aquatic environment: Characterization in terms of steady state kinetics, Journal of Environmental Science and Health, Part B Pesticides, Food Contaminants, and Agricultural Waste 12: 1-11. Doi: 10. 1080/03601234.2015.1067101.
  • P. Dzomba, J. Kugara and M. F. Zaranyika (2015). Extraction of tetracycline antimicrobials from river water and sediment: a comparative study of three solid phase extraction methods. African Journal of Pharmacy and Pharmacology, 9(19): 523-531, doi: 10.5897/ajpp2015. 4341.
  • Dzomba P, Kugara, J, Zaranyika, M. F. (2015) Characterization of microbial degradation of oxytetracycline in river water and sediment using reversed phase high performance liquid chromatography. African Journal of Biotechnology, 14: 1-9 doi 10.5897/AJB2014.14091.
    P. Dzomba, J. Kugara, V. V. Mukunyaidze and M. F. Zaranyika (2015). Biodegradation of tetracycline antibacterials using green algal species collected from municipal and hospital effluents Der Chemica Sinica, 6(7):27-33

2014

  • Dzomba P, Zaranyika M.F, Kugara J, Zhanda T Determination of oxytetracycline residues in untreated and treated drinking water in Bindura town by RP-HPLC-UV visible spectrometry after ultrasonic assisted dispersive solid phase extraction (UA-DSPE), World Journal of Pharmaceutical Research, 2014, 3 (2) 1568-1578.
  • P. Dzomba, I. Gwizangwe, P. Pedzisai, E. Togarepi (2014).Quality, Shelf-life and Sensory Analysis of Beef Meat Treated with Cleome gynandra and Vigna unguiculata Extracts. Chemical Engineering and Science. 2 (3): 40-45.
  • Pamhidzai Dzomba, Cexton Musekiwa (2014). Anti-obesity and antioxidant activity of dietary flavonoids from Dioscorea steriscus tubers. Journal of Coastal Life Medicine. 2(6): 465-470
  • Shasha D, Gwezere W, Dzomba P, Chayamiti T (2014). Determination of Organophosphorus Pesticide Residues in Cabbages from Bindura Market Place by Solid Phase Extraction and Gas Liquid Chromatography. Bulletin of the Environment, Pharmacology. Life Sciences, 3 (3): 95-99

2013

  • Dzomba P and Gwizangwe I. TLC separation, antibacterial and anti-inflammatory activity of extracts derived from Zanthoxylum humile roots. International Journal of Research in Ayurveda and Pharmacy. 2013, 4(4): 482-486 DOI 10.7897/2277-4343.04403
  • P. Dzomba, D. Shasha, T. Chayamiti, G. Murambasvina, N. Mudavanhu. Rationale Behind the Use of Temnocalyx Obovatus Roots as Antivenins Against Snakebites in Primary Health Care. American Journal of Phytomedicine and Clinical Therapeutics, 2013, (1): 098-106
  • Dzomba P, Ngoroyemoto N, Musarurwa R. Antioxidant Capacity and Microbial Attributes of Raw Cow Milk Fortified with Hypotrigona Squamuligera Honey. Global Journal of Medical research Microbiology and Pathology. 2013, 13 (3): 9-12
  • Dzomba P;  Mupa M and Togarepi E. Anthocyanin and antioxidant activities of common bean species grown in Mashonaland central, Zimbabwe. African journal of agriculture research. 2013, 8(25): 3330-3333, DOI: 10.5897/AJAR12.225
  • N. Mudavanhu, P. Dzomba, C. Mudavanhu and S. Mazorodze. Occupational Safety and Environmental Risks Scenario of Small and Medium Enterprises (SMEs): An Analysis of the Situation in Harare Chemical Industries, Zimbabwe. American Chemical Science Journal, 2013 (3) 2: 98-110
  • N. Mudavanhu, P. Dzomba and L. D. Mudehwe. Potential Devastating Domino Effect: A Case Study of Msasa Industrial Area, Zimbabwe. American Chemical Science Journal. 2013; 2: 56-57.
  • D. R. Masvodza, P Dzomba, F. Mhandu and B. Masamha. Heavy Metal Content in Acacia saligna and Acacia polyacantha on Slime Dams: Implications for Phytoremediation, American Journal of Experimental Agriculture 2013, 3(4): 871-883.
  • Ngoroyemoto N, Mushore J, Dhliwayo, J and Dzomba P. Antimicrobial Properties of Methanolic, Water And Chloroform Extracts of Psidium Guajava (L) Roots. International Journal of Green and Herbal Chemistry. 2013, 2, (3): 713-722.
  • Mupa M, Dzomba P, Musekiwa C, Muchineripi R, Lead Content of Lichens in Metropolitan Harare, Zimbabwe. Air Quality and Health Risk Implications, Greener Journal of Environmental Management and Public Safety, 2013, 2(2), 075 – 082,

2012

  • Dzomba P, Mupa M, Wild Cucumis Anguria Leaves: Phytochemical Profile and Antioxidant Capacity Asian Journal of Tropical Biomedicine, 2012, 1 – 5.
  • Dzomba P, E Togarepi, C Musekiwa. Phytochemicals, antioxidant and antibacterial properties of a lichen species Cladonia digitata. African Journal of Biotechnology. 2012 11(31):7995-7999.
  • P Dzomba, N Muchanyereyi. Potential Antimicrobial plant extract based therapeutics from Temnocalyx obovatus roots. European journal of medicinal. 2012, plants 2 (3): 209-215
  • Dzomba P, Togarepi E, Musekiwa C, Chagwiza CJ. Improving oxidative stability of soya and sunflower oil using Temnocalyx obovatus extracts. African Journal of Biotechnology.  11(50: 11099-11103
  • E Togarepi, C Mapiye, N Muchanyereyi, P Dzomba. Opitimisation of Fermentation Parameters for ethanol production fron Ziziphus mauritiana fruit pulp using Saccharomyces cerevisiae (NA33). International Journal of biochemistry research and review.2012. 2(2): 60-69
  • Dzomba, P.; Togarepi, E.; Mahamadi C.  In-vitro assessment of antioxidant potential and phenolic capacity of Temnocalyx obovatus leaves. African Journal of Biochemistry Research. 2012. 6(8), 98-104, 30.
  • P Dzomba, S Nyoni, N Mudavanhu. Heavy metal contamination risk through consumption of traditional food plants growing around Bindura town,Zimbabwe. Journal of Toxicology and Environmental Health Sciences. 2012. 4(5): 92-95.
  • P. Dzomba, T. Chayamiti, S. Nyoni, P. Munosiyei and I. Gwizangwe.Ferriprotoporphyrin IX-Combretum imberbe crude extracts interactions: Implication for malaria treatment.  African Journal of Pharmacy and Pharmacology. 2012,  6(29): 2205-2210,
  • P. Dzomba N. Ngoroyemoto L. Mutandwa, D. Shasha. Phytochemical screening and biological activities of Hypotrigona squamuligera raw honey. International Journal of Biochemistry Research & Review. 2012,2(3): 98-105.
  • P. Dzomba, T. Chayamiti and E. Togarepi (2012) Heavy Metal Content of Selected Raw Medicinal Plant Materials: Implication for Patient Health, Bulletin of Environment, Pharmacology and Life Sciences, 1(10), 28-33.

2011

  • C Mahamadi, E Togarepi, P Dzomba. Extraction of phenolic compounds from Temnocalyx obovatus. African Journal of Biotechnology. 2011 10(54):11245-11248

2008

  • Ngarivhume, T., Dzomba  P., Gwizangwe, I., Zendera, C.H., Katsvanga, C.A.T., Jimu, L., Moyo, M. and Chagonda, T Anaesthetic effects of Adenia gummifera distillates on Apis mellifera (Honeybee). Natural Products Research 2008, 22 (15): 1370-1378.

Conferences and Exhibitions

  • Pamhidzai. Dzomba and  Mark F. Zaranyika.  The term bioavailability;
    current and proposed definition: insights from persistence of
    tetracyclines antibiotics in the aquatic environment. The 13th ANCAP virtual Symposium. 21nd – 23 December 2020
  • Pamhidzai Dzomba and Mark F. Zaranyika Kinetic and statistical
    thermodynamic analysis of the degradation of tetracycline hydrochloride
    in the aquatic environment under sub-tropical Conditions. The 13th ANCAP virtual Symposium. 21nd – 23 December 2020
  • Pamhidzai Dzomba and Mark F. Zaranyika. Dissipation of
    Chlortetracycline in the Aquatic Environment: A generalized Multi-Phasic
    Pseudo-Zero Order Rate Law, The Twelfth ANCAP Symposium, University of Dar es Salaam, Tanzania, 2nd – 4th December 2019
  • Pamhidzai Dzomba and Mark F. Zaranyika Bioaccessibility of tetracycline antibiotics to higher fauna in the aquatic environment:
    Effect of speciation, The Twelfth ANCAP Symposium, University of Dar es Salaam, Tanzania, 2nd – 14th December 2019
  • P. Dzomba, T. Chidavayenzi, E. mwanza, Formulation of food based alternative remedies for diabetes T 2. 10th International conference of the African Materials Research Society, AMRS Arusha, Tanzania, 2019, 10-13 December. 
  • H. Rambwawsvika, P. Dzomba, L. Gwatidzo. Formulation of an anti-alopecia cream from Dicerocaryum senecioides flavonoids. 10th International conference of the African Materials Research Society, AMRS Arusha, Tanzania, 2019, 10-13 December.
  • Pamhidzai Dzomba, Estele Mwanza. Dipeptidyl peptidase IV and α-glucosidase inhibitory activity of four bush okra species: implication for ethinobotanical management of diabetes type 2. International Conference of the Natural Products Research Network for Eastern and Central Africa – Kenya (NAPRECA – K). 8 – 10, February 2018; SAJOREC, JKUAT, Kenya
  • Pamhidzai Dzomba and Tinevimbo Chidavayenzi, Inhibition of α-amylase by Euclea crispa phytochemicals: Implication for herbal management of diabetes mellitus type 2 , 9th International Conference of the African Materials Research Society. 9 t h – 1 4 t h D E C 2017 – Gaborone, Botswana
  • P. Dzomba, J. Kugara M. F. Zaranyika. Speciation and degradation of tetracycline in the aquatic environment: characterization in terms of steady state kinetics that takes into account photolytic, hydrolytic, microbial degradation and adsorption onto colloidal and sediment particles.10th ANCAP Symposium, from 2nd– 4th December 2017, Mombasa, Kenya
  • M. F. Zaranyika*, P. Dzomba and J. Kugara. Speciation and persistence of chlortetracycline in the aquatic environment: Characterization in terms of a linear rate law. 30-31 July 2015, ANCAP Symposium. Makerere University, Uganda. Www.Ancapnet.Org/Symposium.11.Htm
  • Pamhidzai Dzomba, Mark F. Zaranyika, JamesonKugara. (2013).Determination of oxytetracycline residues inuntreated and treated drinking water in Binduratown by RP-HPLC-UV visible spectrometry afterultrasonic assisted dispersive solid phaseextraction (UA-DSPE).1-2 September 2013 SETAC 6th Conference Lusaka Zambia. Www.Setac.Org/Event/Africa-2013
  • Ngarivhume, T., Dzomba, P., Gwizangwe, I., Zendera, C.H., Katsvanga, C.A.T., Jimu, L., Moyo, M. and Chagonda, T Anaesthetic effects of Adenia gummifera distillates on Apis mellifera (Honeybee). Zimbabwe Agriculture Show. ZAS 2009. Harare Exhibition Park
  • P. Dzomba, I. Gwizangwe and P. Pedzisai.Quality, Shelf-life and Sensory Analysis of BeefMeat Treated with Cleome gynandra and Vigna unguiculata Extracts, 2013, Intellectual Property Explo 2012. University of Zimbabwe
  • Dzomba P. Development of bio-veterinary drugs from indigenous medicinal plants.Zimbabwe Agriculture Show. ZAS 2013. Harare Exhibition Park
  • Dzomba P.Use of virtual laboratories in the teaching of science at high school level.IST Internationa Science and  Mathematics Education Conference, Bindura University August 2013
  • Dzomba P. Development of safe and environmentally friendly household chemicals.Zimbabwe International Trade Fair. ZITF 2016. Bulawayo ZITF Exhibition Park
  • Ngarivhume, T., Dzomba, P., Gwizangwe, I., Zendera, C.H., Katsvanga, C.A.T., Jimu, L., Moyo, M. and Chagonda, T Anaesthetic effects of Adenia gummifera steam distillates on Apis mellifera (Honeybee).Intellectual Property Explo 2010.University of Zimbabwe. Poster presentation

Workshops

  • Use of biomarkers and bio-indicators in the analysis of persistence organic pollutants in the environment. 26-31 August 2013. ANCAP 10th summer school. University of Zambia. Lusaka.www.ancap.org/summer10.htm
  • Analysis of persistent organic pollutants (POPs) 24 February 2014 Oasis Hotel, Zimbabwe
  • Process oriented statistical analysis and use of the RZWQM2 model to predict fate and transport of organic molecules in the soil. 27-31 July 2015. ANCAP 11TH Summer School. Makerere University. www.ancap.org/summer 11.htm

Awards

  • Vice Chancellor Award For Best Researcher, 2012
  • Book Prize For Best Presentation, (SETAC 6th Conference)
  • Money Prize For Second Best Presentation, ANCAP Symposium. Makerere University, Uganda. www.ancapnet.org/symposium.11.htm