Prof. Silvia C. Diaz Llera

professor llera diazAcademic Profile
Degree in Biological Sciences graduate, specialized in Genetics (University of Havana)
PhD in Pharmaceutical Sciences, Genotoxicology. (University of Havana)

Contact Details

Phone number: +263779305303

Recent research publications

  1. Ansoar Rodríguez Y, Díaz Llera S, Rodeiro Guerra I, Frión Herrera Y, Morffi Figueroa J, Martínez D, Menéndez R. DNA damage in NMRI mice treated with the aqueous extract of the marine plant Thalassia testudinum. Pharmacology 2010. Vol.19. Suplement 2. 2010.
  2. Ansoar Rodríguez Y, Díaz Llera S, Rodeiro Guerra I, Frión Herrera Y, Morffi Figueroa J, Martínez D, Menéndez R. Evaluation of the DNA damage using the Comet assay in mice treated with the aqueous extracto of the marine plant Thalassia testudinum. Revista Cubana de Investigaciones pesqueras. VI International Worlshop CONyMA. ISBM 978-959-300-008-6. 2010.
  3. Gregorio Martínez-Sánchez, Silvia Menéndez-Cepero, Mirta Copello, Silvia Díaz-Llera, Lamberto Re (2012). Rectal insufflations are a valid way in ozonetherapy. Revista Española de Ozonoterapia. Vol. 2, nº 1, 74-86.
  4. Genotoxic potential of BM-21, an aqueous-ethanolic extract from Thalassia testudinum marine plant by Y. Ansoar, S. Díaz, J. Piloto, J. Morffi, M.J. Gómez-Lechón, E. Almeida, Y. Frión, R. Menendéz, D. Martínez, M.D. Fernández, I. Rodeiro. Journal of Pharmacy & Pharmacognosy Research, 2 (6), 183-193, 2014
  5. Ansoar Rodríguez, Yadira, Fontanetti, Carmen S., Christofoletti, Cintya A., Díaz Llera Silvia del C. Aplicaciones del ensayo Cometa en Genética Toxicológica Revista CENIC Ciencias Biológicas, Vol. 46, No. 1, pp. 51-62, enero-abril, 2015.

Summary of major research projects

  1. Genotoxic evaluation of drugs, therapies or active principles, IPFS, Dept. Pharmacology and Toxicology. Head: S. Díaz Llera, 1993-1997.
  2. Mutagenic potential of reactive oxygen species by pharmacologic agents in biological systems. Collaborating institutions: Dept. Pharmacology and Toxicology, IPFS, UH (Head: S. Díaz Llera) and Environmental Mutagenesis Lab., Biomedical Research Institute of the National Autonomous University of Mexico (Head: P. Ostrosky-Wegman). 1996-97
  3. Safety and toxicology of herbal remedies used in south-western Uganda. Propiedades farmacológicas y evaluación toxicológica de productos naturales: Vernonia amygdalina PhD supervisor, MUST, Mbarara, Uganda. 2005-2008.
  4. Study of the genotoxicological properties and chemoprotective activity of Cuban natural products extracts and main constituents used in folk medicine for the treatment of cancer and degenerative diseases, 2008-2012.
  5. Evaluation of natural products of therapeutic interest for cancer treatment: Selective cytotoxicity, cyto and genoprotection, antitumoral and antimetastasic activity. CAPES/Brazil – MES/Cuba program. 2012-2014.


  • 43 years of teaching experience in higher education.
  • Main courses taught: Genetics, Cell and Molecular Biology and Genetic Toxicology.
  • Author of Syllabuses for Technical, Higher Education, and Postgraduate Education.
  • Supervisor of Degree, MSc and PhD Research projects.


  • Acknowledgment Medal: “Por la Educación Cubana” (For the Cuban Education) from the Ministry of Education, Dec. 22, 1990.
  • Annual award from the Rector of the University of Havana dedicated to the “Scientific result of greatest economic significance already applied” for the study Biobras 16, a new Cuban bioregulator. Studies for registration and marketing Jan. 31, 1997.
  • Award received in the category of “Already applied result with greatest contribution to social development”, Jan 2000
  • Acknowledgment to the University Excellence from the Dean of the Pharmacy and Nutrition Faculty of Havana University. Dec. 1997.
  • PhD thesis awarded by the Scientific Council of the Pharmacy and Nutrition Faculty of Havana University, 2000.
  • PhD thesis awarded by the University of Havana Scientific Council, 2000.