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    Underlying pathology also may play a role in the survival of patients with FTLD. Other factors linked to a shorter survival are mutism, dysphagia, neurological abnormalities (e.g., where to buy viagra uk yahoo parkinsonism, primitive reflexes, incontinence, and seizures) (Hodges et al., 2000). Roberson et al., 2003).

    Patients with NFPA live closer to 3.4 years, whereas patients with SD have the longest survival. Patients with Kreutzfeldt–Jakob disease show cortical ribboning and basal ganglia changes with fluid-attenuated inversion recovery (FLAIR) and diffusion-weighted imaging, and have a much more rapid disease course (Meissner et al., 2002.

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    Transcranial magnetic stimulation, when applied to the DLPFC 2 seconds after presentation of the locations to be remembered, significantly alters the amplitude of subsequent memory-guided saccades in normal humans Frontal Lobe Motor Control and Voluntary Eye Movements 257 tions to the SNr, the SC integrates information regarding the reward value of saccades to specific locations. Mosimann, Felblinger, Ballinari, Hess, & Muri, 2001), and difficulties with saccade programming in Alzheimer’s disease may be in part explained by damage to this cholinergic circuit. Decreased attention and visual search efficiency (Daffner, Scinto, Weintraub, Guinessey, & Mesulam, 1990.

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