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  • RESEARCH 4 BUSINESS 2016, Ljubljana, 5 and 6 of May 2016

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    This assay is typically performed on peripheral blood 142 Paquette, Hiller, and Munker viagra voucher free and is much more sensitive than standard cytogenetic studies to assess disease response. The quantitative PCR (Q-PCR) assay for the BCR-ABL translocation can detect up to a 4.7-log reduction in transcript levels. FISH for the BCR-ABL translocation typically evaluates 190 cells.

    Although cytogenetic response is important, standard chromosomal analysis evaluates only 20 cells. At least 80% of patients who reach this endpoint do so within the first year of treatment.