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  • These second neoplasms have been called the “price of success” viagra online us and can be observed in about 21% of patients after 18-yr follow-up. A significant problem emerging in recent years is the appearance of other malignant tumors in patients cured of HL. Some types of second tumors are associated with special treatment features and appear preventable.

    A rare but serious late effect of splenectomy was septicemia caused by pneumococci. The risk of second malignancy is viagra online us about three- to fivefold elevated, compared with the general population. The major types of second cancers are acute myelogenous leukemias , myelodysplastic syndromes, NHLs, and various solid tumors.

    The late complications of treatment mandate a lifelong follow-up of patients treated for HL, despite the generally good prognosis. This may be prevented to a large extent by immunizing such patients against pneumococci 266 Hiller and Munker prior to splenectomy.

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    Furthermore, New and colleagues reported on a lack of activation in the left anteriomedial orbital cortex in response to mCPP in patients with impulsive aggression, but not in their age- and sexmatched controls viagra online us. Researchers in the field of suicide prevention admit that 5-HT is involved through its inhibi- Serotonin and the Frontal Lobes 187 tory function on other neuronal systems (Golden, Gilmore, & Carson, 1992), but it remains unclear whether this is a trait or a state feature of suicide attempters (Abbar, Amadeo, & Malafosse, 1989). Therefore, the difficulty in modulating aggressive impulsive behavior may be a consequence of the decreased activation of inhibitory regions in response to a 6-HT-ergic stimulus. Recently, New and colleagues (2001) replicated previous studies in a much larger sample and found a blunted prolactin response to d,lfenfluramine of male, but not female, patients with personality disorders in relation to impulsive aggression and to suicide attempts.

    This gender effect has been often reported and is specific to impulsivity and aggression, and independent of the diagnosis of borderline personality disorder (Soloff, Kelly, Strotmeyer, Malone, & Mann, 2002).