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    These authors found that patients with subcortical lesions that viagra online kaufen schweiz involved the basal ganglia or thalamus, but spared the subcortical white matter tracts exiting the frontal lobes, do not lead to impairments on the antisaccade task. Neurons in the SNr, acting as the output of a basal ganglia circuit, might also help to suppress saccade-related activity in the SEF and FEF during the antisaccade task. However, a recent analysis Frontal Lobe Motor Control and Voluntary Eye Movements 273 of brain lesions in human patients with saccade impairments suggests that this basal ganglia circuit is less important for reflexive saccade suppression than other brain regions (Condy et al., 2000). In addition to possible stimulatory roles of the SEF on antisaccade generation, SEF neurons may also inhibit the FEF and SC during the preparatory set prior to an antisaccade.

    This hypothesis is supported by increased fixation-related neuron activity in the SEF prior to target presentation, with decreased activity of these same neurons when a direction error is made (Schlag-Rey et al., 1997).