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    As an aside, brain vasopressin 1a receptors are known for their role in mammalian pair bonding and are densely present on layer 4 pyramidal neurons of the ACC, including viagra medical benefits the newly evolved VENs. At a nonconscious level, the supraoptic and paraventricular hypothalamic nuclei project to the posterior pituitary, which sends a blood-borne chemical message—arginine vasopressin—to the kidneys, instructing them to retain water. 2000, egan et al.. Simultaneously, the hypothalamus communicates directly and indirectly with the thalamus and paralimbic cortex (including the ACC and insula, see Figure 18.1) to bring the situation to mind and promote water-seeking behavior (de Araujo, Kringelbach, Rolls, & McGlone, 2000.

    1999), sewards & Sewards.