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    All these observations lead to the conclusion that the Class II, Ig-bearing B cell can play an important role in viagra manila for sale antigen presentation. ANTIGEN UPTAKE, PROCESSING AND PRESENTATION 37 Gut epithelial cells Entry of antigen through mucosal surfaces and its subsequent processing and presentation may occur through a number of routes (Nicklin, 1986). The release of lymphokines by T cells can subtly regulate the APC capacity of B cells, thus. Indeed recent evidence from experiments using B-cell depleted mice have suggested that the B cell may play a major role in antigen presentation and clonal expansion of activated T cells within lymph nodes (Ron and Sprent, 1987).

    The specificity of the antibody will be identical to that of the surface Ig of the B cell used to capture the native antigen. Under the influence of these and other T-cell derived factors, the B cell is also able to proceed along the pathway of differentiation, maturing into an antibody-producing plasma cell.

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