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    Direct measurement of lymphocyte or effector cell numbers in the host or at the site of infection are also ways of evaluating the host potential for responding.

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    • Digital rectal exam is mandatory for all patients with LGIB to evaluate for prolapsed internal hemorrhoids or masses and to characterize the color and consistency of blood/stool in the rectal vault. On the other hand, through dilutional effects from crystalloid hydration, the hematocrit may be seen to decrease—even in the absence of ongoing active bleeding. However, early in presentation, the hematocrit is likely to underestimate the degree of blood loss due to volume contraction.

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