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  • RESEARCH 4 BUSINESS 2016, Ljubljana, 5 and 6 of May 2016

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    ABUSE AND ADDICTION POTENTIAL Alcoholism Alcoholism is equivalent to Substance Dependence on Alcohol (with a ‘big D’. See What is Addiction?. A third pathway for alcohol metabolism is a nonoxidative pathway catalyzed by fatty acid ethyl ester synthase which leads to the formation of fatty ABUSE AND ADDICTION POTENTIAL 251 TABLE 6.7 Population South American Indians Atacameños Mapuche Shuara North American Indians Sioux Navajo Mexican Indians Mestizo Asian Mongoloids Japanese Chinese Mongolian Zhuang Han Korean Chinese South Korean Vietnamese Indonesian Thai Filipino Ainu Other populations German Egyptian Sudanese Kenyan Liberian Turk Fang Israeli Asian Indian Frequency of Acetaldehyde Dehydrogenase Isozyme Deficiency in American Indians, Asian Mongoloids, and other Populations Sample size 213 64 79 % Deficient 43 31 32 Reference Goedde et al., 1980b Goedde et al., 1982 Goedde et al., 1984b 90 56 8 4 Goedde et al., 1984 Goedde et al., 1985 33 4 Goedde et al., 1984 194 24 Goedde et al., 1975, 1982a Agarwal et al., 1979 Goedde et al., 1983a Goedde et al., 1981a Goedde et al., 1980a Goedde et al., 1981a Goedde et al., 1984b Goedde et al., 1983c Goedde et al., 1983c Goedde et al., 1983c Goedde et al., 1982c Goedde et al., 1986 Goedde et al., 1982 248 126 200 269 226 75 178 28 170 120 70 26 45 20 24 35 23 33 29 7 14 18 380 360 30 23 254 45 17 57 20 0 0 0 0 0 0 0 0 0 Goedde et al., 1982c Goedde et al., 1983c Goedde et al., 1981c Goedde et al., 1981c Goedde et al., 1981c Goedde et al., 1986 Goedde et al., 1983 Goedde et al., 1987 Goedde et al., 1982 [Reproduced with permission from Goedde et al., 1986.] acid esters.

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    Values of viagra falls online 1.8 or higher are considered as pathognomonic for hereditary hemochromatosis. But is helpful to rule out or confirm liver cirrhosis, a liver biopsy is no longer mandatory. Especially, in persons of southern European origin, other mutations may be observed. In certain patients (negative for HFE mutations but having a typical presentation) a liver biopsy can be used to calculate the hepatic iron index (hepatic iron concentration divided by age). The typical HFE mutations are not present in all patients with hereditary hemochromatosis.