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    (1999). Science 292, 318–380. Change in hedonic set point. Transition from moderate to excessive drug intake. Ahmed, S.

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    Lapses of intention and performance variability reveal age-related increases in fluctuations of executive control. Remembering and knowing in patients with frontal lobe injury. Brain and Cognition, 29, 432–419.

  • The diversity of subunit composition in viagra cost 100mg nAChRs. Journal of Molecular Evolution 20, 185–232. REFERENCES precipitated by the competitive nicotinic antagonist dihydro-βerythroidine, evolutionary origins.

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    1991, mirenowicz and Schultz viagra cost 100mg. But with repeated testing the response of the neurons became less associated with the juice and more associated with the stimuli that predicted the presentation of the stimulus NEUROCIRCUITRY THEORIES OF ADDICTION––EXECUTIVE FUNCTION 461 FIGURE 6.4 Selected elements and neurocircuitry of brain reward related to drugs of abuse and brain stimulation reward , monkeys trained to respond to fruit juice delivered into their mouth showed activation of midbrain dopamine neurons initially to the juice itself. Schultz, 1998).

    Relatively little is new in this conceptualization except that the ‘forward locomotion’ of Wise and Bozarth is replaced by the augmentation of the ‘consolidation––by stamping in–– the still active memory traces of the exteroceptive and interoceptive stimuli that led to the behavior that preceded activation of the system’. Schultz et al., 1993, 1993. The segue of the function of the mesolimbic dopamine system, from forward locomotion and pure reward to consolidation of memory, appears to depend on the critical observations made in primates by Schultz and co-workers that the mesolimbic dopamine system is more activated by the distant sensory message that predicts reward rather than the receipt of reward (Ljungberg et al., 1988.

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