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    Dopamine neurons also have been the target of many of the imaging studies devoted to neurotransmitters, transporters, and receptors, presumably because of both a limited conceptual framework (see Neurobiological Theories of Addiction and Drug Addiction. Acute administration of cocaine and alcohol has been shown to enhance dopamine release in the ventral striatum as measured by imaging studies.

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  • 2004) have encouraged an interest in their viagra cheap uk use for FTLD, tariot et al.. However, there is no evidence for a cholinergic deficit associated with any subtypes FTLD, and in our experience, cholinesterase inhibitors can precipitate worsening of behavior. Several treatment studies with the new NMDA receptor blocker, memantine, are under way.

    Trinh, Hoblyn, Mohanty, & Yaffe, 2001). 1999, tariot viagra cheap uk et al.. Despite the absence of a strong scientific rationale for NMDA-blockers, the recent successes with these compounds in slowing progression of AD (Reisberg et al., 2002.

    There is a profound loss of glutamatergic neurons in frontal cortex in FTLD (Ernst, Chang, Melchor, & Mehringer, 1993), but no data suggest that the mechanism for this loss is via excessive excitotoxic activity at the level of N-methyl-D-aspartate (NMDA) receptors. Therefore, we do not recommend these compounds for either the cognitive or behavioral disorder associated with FTLD.

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