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    37:25–41. Harris L, McKenna WJ, Rowland E, Krikler DM. Side effects of longterm amiodarone therapy.

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  • PDE-5 is the primary enzyme that catalyzes the 2 Eduardo Fernández-Martínez viagra capsules in delhi Figure 4 Some structures of thalidomide analogs. The first group is composed by molecules structurally and functionally very similar to Tha, known as immunomodulatory drugs because of their marked costimulatory properties on T cells promoting the secretion of IL-4 and IFN-γ, but these compounds also inhibit the production of IL-1β, IL-6 and IL-12 as well as greatly increase the synthesis of IL-11, the main antiinflammatory Th2-type cytokine in stimulated PBMC (Corral et al., 1998. The most important members of this immunomodulatory group are pomalidomide (CC-4087, Actimid™) and lenalidomide (CC-5013, Revlimid™) (Teo, 2001). Both drugs belong to a novel generation of amino-substituted Tha analogs in the phthalimide ring (Muller et al., 1998) (Figure 3). Muller et al., 1995), they also increase IL-6 (Marriott et al., 1995.

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