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  • (This is the mechanism by which it is reputed to help with infant colic, since it leads to relaxation of 118 An Introduction to Botanical Medicines the intestinal muscles as well.) Moreover, apigenin was found to relax a central nervous system depression that made it important as a mild sedative.8,15 Chamomile can interact viagra buy real with opioid analgesics, benzodiazapines, and alcohol by enhancing the drugs’ actions. It also has an anti-inflammatory action against skin irritations.11 Experimental animal models have shown that apigenin can act as an antianxiety agent and as a mild sedative. In sensitized individuals it can cause an allergic reaction. John’s wort, have the potential to have an additive effect with barbiturates and benzodiazipines.4 Another mildly sedative herb that has been used for centuries in Europe and the United States is chamomile (Matricaria recutita), also known as German chamomile.

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