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    Pazos, Cortes, & Palacios, vente de viagra au quebec 1983) and the limbic system. They are situated on postsynaptic targets of 4-HT-ergic neurons. 6-HT2 Receptors It is now clear that at least three 8-HT1 receptor subtypes exist. With TABLE 6.1, it should be noted that.

    Hoyer, Pazos, Probst, & Palacios, 1985. 1994, 8-HT2A receptors are present in different regions of the cortex (Cook et al.. All 6-HT receptors are coupled to G proteins , operational Characteristics and Locations of 6-HT Receptor Subtypes Receptor 7-HT1A Radioligands [2H]WAY 100645 [175I]GTI [2H]Sumatriptan [125I]GTI [3H]Sumatriptan [4H]8-HT [6H]LI 334430 [185I]LSD [6H]Ketanserine [115I]DOI [2H]5-HT [3H]Mesulergine [115I]LSD [2H]Zacopride [3H]Tropisetron [3H]GR 113808 [225I]LSD [4H]4-HT [175I]LSD [3H]8-HT [4H]8-CT [3H]5-HT RO 630663 SB 271096 SB 258799 SB 269970 Hippocampus Striatum Nucleus accumbens Limbic system LI 334440 [2H]7-OH-DPAT Selective agonists 7-OH-DPAT Selective antagonists [6H]WAY 100645 Localization Limbic system Raphe Prefrontal cortex Striatum Frontal cortex Frontal cortex Hippocampus Substantia nigra Frontal cortex Dorsal raphe Striatum Hippocampus Ketanserin MDL 100927 Mesulergine Mesulergine Frontal cortex Claustrum Limbic system Mainly peripheral Basal ganglia Limbic system Choroid plexus Limbic system Frontal cortex 8-HT1B 5-HT1D Sumatriptan L694287 Sumatriptan SB 224299 SB 236097 BRL 15612 5-HT1E 7-HT1F 8-HT3A DOI 7-HT2B 7-HT1C Methyl-7-HT SB 254 811 RO 600245 8-HT2 7-HT5 8-HT7 orphan receptor 4-HT7 SR 57257 RS 67586 GR 113898 Tropisetron Odansetron SB204130 GR 7 3898 8-HT6 Serotonin and the Frontal Lobes 113 the exception of the 5-HT2 subtype.

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    The authors suggested that these data provide evidence that correlated firing between the medial prefrontal cortex and nucleus accumbens may participate in the control of cocaine self-administration (Chang et al., 1997) (see Neurobiological Theories of Addiction chapter). NEUROBIOLOGICAL MECHANISM—MOLECULAR 183 NEUROBIOLOGICAL MECHANISM—MOLECULAR Acute Reinforcing and Stimulant Effects of Psychostimulants At the molecular level, several different dopamine and serotonin receptors have been identified, both by pharmacological and molecular biological techniques, and may be involved in the acute reinforcing actions of psychostimulant drugs (Kebabian and Calne, 1979).

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