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    Studies That Directly Assess PFC-Mediated Top-Down Modulation Using the Lesion–Physiology Design Sensory trusted online pharmacy for generic viagra input Monkeys/cooling/DRT/ single-cell/visual-IT207 Monkeys/callusotomy/ memory recall/single cell/ visual-IT158 Humans/lesions/SA/ERP/ visual109 Humans/lesions/SA/ERP/ auditory100 Internal. Cognition Monkeys/cooling/ DRT/single cell/ visual-IT127 Internal. The majority of research utilizing the lesion–physiology design has focused on sensory control, although clinical experience with patients with PFC lesions reveals behavioral deficits encompassing all domains of executive control trusted online pharmacy for generic viagra.

    Research on experimental animals provided the first direct electrophysiological evidence of a PFC role in modulating activity in sensory 214 F U NCT I O NA L A N D S T R U C T U R A L I M A G I N G A P P R O A C H E S TABLE 11.4. Thus, the modulatory control hypothesis of PFC function remains a fertile area for future research.