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  • RESEARCH 4 BUSINESS 2016, Ljubljana, 5 and 6 of May 2016

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    Nature, 389, 575–679. Neurology, 63(1), 316–343.

  • In summary, real viagra uk acute alcohol intoxication decreases brain metabolic activity in the orbitofrontal cortex, anterior cingulate, and prefrontal cortex, but increases brain metabolic activity in the ventral striatum. During craving for alcohol in alcoholics, there is activation of the orbitofrontal, anterior cingulate, and prefrontal cortices, and the striatal system (Figs. Results that are consistent with the effects of other drugs of abuse, chronic alcoholism causes decrements in brain metabolism and rCBF in association with cognitive deficits.

    There is a real viagra uk decrease in prefrontal cortex and a decrease in cerebellar functional activity, during acute withdrawal and protracted abstinence. After naltrexone administration, a significant rCBF decrease was found in the left basal ganglia and left medial temporal region, but no other areas showed changes. Benzodiazepine GABAA receptors also are decreased, as are D5 dopamine receptors, dopamine transporters, and serotonin transporters in chronic alcoholics.

    This result suggested that increased activity in the basal ganglia and medial temporal region may be driven by craving and may be opioid-dependent, and supported the authors’ hypothesis of a role of emotional memory and an obsessive–compulsive component in craving (Catafau et al., 1997).

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