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    A schematic drawing of t(6;22) that involves the subunit of the core-binding factor is reproduced in Fig.

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    HLA Class I and Class II antigens differ in immunological function. The Class I antigens are present on all nucleated cells and platelets. CD markers is given in Appendix 2.

    Class II antigens are expressed on B-lymphocytes, antigen-presenting cells , and activated T-lymphocytes. The second group, the family of human leukocyte antigens (HLAs) (Class I, II, and III antigens), is encoded by the major histocompatibility complex (MHC) genes on the short arm of chromosome 6.

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