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  • They do not mount a suitable protective anti-parasite response, and it is plausible to suggest that a vaccine composed of parasite antigens which should stimulate a good protective response (by definition assessed in price for viagra 50mg terms of a resistant individual’s immune response) may not be effective. However, such individuals are not those who would benefit most from successful vaccination. The segregation of a population into relatively resistant or susceptible individuals carries a number of implications with regard to vaccination strategies. Given uniform exposure to parasite transmission stages, individuals with low numbers of parasites may be considered to be resistant and are either innately refractive to infection or mount a strong, protective acquired immune response. Will not show marked pathology and should respond well to vaccination because they are genetically equipped to respond to parasite antigens in a host-protective manner, these subjects will not make a large contribution to parasite transmission in nature.

    With the recent advances in molecular genetics and immunology, it may be possible in the foreseeable future to predict which individuals are likely to be susceptible or resistant to particular parasitic diseases and to attempt appropriate vaccination. It is the susceptible proportion in the population, who have high parasite burdens and show severe disease symptoms, who more urgently require assistance in coping with their parasite burdens. However, a note of caution.

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