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  • The SC forms a pfizer viagra to buy critical node in the network for incorporating reward information into the generation of eye movements. Recent monkey data also support a role for these and nearby regions in mental rehearsal of eye movements, prior to actual saccade initiation (Cisek & Kalaska, 2002). Via a basal ganglia circuit, which includes the oculomotor portions of the caudate nucleus, with projec- Dorsolateral Prefrontal Cortex The dorsolateral prefrontal cortex (DLPFC) is involved in multiple aspects of saccade programming, including making decisions to initiate voluntary saccades and maintaining spatial working memory for target locations (Funahashi, Chafee, & Goldman-Rakic, 1993. Pierrot-Deseilligny et al., 2003). Neurons that are downstream of these signals, in midbrain and pontine oculomotor nuclei, have firing rates that directly correlate with the speed and amplitude of saccades.

    Upward saccades are represented medially and downward saccades, laterally, within the SC (Sparks, 2001). These neurons have monosynaptic excitatory inputs to neurons in the brainstem that inhibit eye movements. Pierrot-Deseilligny, Muri, Rivaud-Pechoux, Gaymard, & Ploner, 2001.

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