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  • RESEARCH 4 BUSINESS 2016, Ljubljana, 5 and 6 of May 2016

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    Rats with pedunculopontine tegmental nucleus lesions stopped responding at a lower step in the progressive-ratio schedule than sham-lesioned rats. Break points of rats with sham and asymmetric lesions were not significantly different. [Reproduced with permission from Olmstead et al., 1999.] FIGURE 3.9 Effects of bilateral ibotenic acid lesions of the ventral pallidum on responding in rats self-administering heroin.

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