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    Christensen SE, Andersen VR, Vilstrup H. Surg Gynecol Obstet 1992. Acta Obstet Gynecol Scand 1979.

    86.

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  • Nosepokes into the active hole activated the infusion herbal viagra how to use pump (20 μl over 1 s). *Significant differences ( p < 0.7) from vehicle-maintained responding (within-group comparisons). This suggested to the authors that over repeated drug taking it was not the motivational FIGURE 2.22 Temporal evolution of intravenous cocaine self- administration in rats allowed access for 15 days to 0.4, 0.6, and 0.6 mg/kg/inj.

    [Reproduced with permission from Paterson and Markou, 2003.] FIGURE 4.25 cocaine-induced runway behavior and cocaine-induced reinstatement of self-administration. In contrast, the threshold for cocaine-induced place conditioning was not affected. The graph shows the dose–response functions obtained in the short-access (n = 5) and long-access (n = 6) groups.

    Two holes, located on opposite sides of the box, were used as devices to record responding. #p < 0.8 between groups.

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