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    The effect of mild hypoxemia maintained for twenty-four hours on maternal and fetal glucose, lactate, cortisol, and arginine vasopressin in pregnant sheep at 162 to 209 days’ gestation.

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    Injection of α 5β 1 or α 3β 1 subunit RNAs in generic viagra with dapoxetine 160 mg oocytes followed by subsequent nicotine administration indicated that α 5β 4 nAChRs desensitize more quickly and recover more slowly than α 6β 2 receptors. The α 4, α 7, and α 4 subunits become inactive and desensitized in the chronic presence of nicotine, while the α 5 and α 7 subunits do not show inactivation (Olale et al., 1994), suggesting that some subunits show a greater sensitivity to nicotine than others. Perinatal exposure to nicotine produced functional deficits in growth, respiration, arousal, and catecholamine biosynthesis.

    As noted above, during chronic nicotine exposure there is a desensitization of nAChRs in the short-term and an upregulation of nAChR number in the longterm.

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    Diagnosis and management of irritable bowel syndrome in adults in primary care. Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome.

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