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  • RESEARCH 4 BUSINESS 2016, Ljubljana, 5 and 6 of May 2016

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    But promising results indicate that both overall survival and relapsefree survival are improved in younger patients when treated with a combined approach, the advantage of adding rituximab to CHOP cheap viagra singapore chemotherapy has mainly been demonstrated in older patients. High-dose therapy with stem cell or bone marrow support is indicated for certain high-risk patients with largecell lymphomas. The chimeric monoclonal antibody rituximab should be added to CHOP, in patients with a B-lineage phenotype. About 40–50% of the patients obtain a complete remission and approx 35% are cured, with this approach. Patients with localized disease are cheap viagra singapore treated with a shorter course of chemotherapy and involved-field radiation.

    Treatment The treatment of large-cell lymphomas depends on the stage of disease. Again, the prognosis seems to be improved when immunotherapy with rituximab is added to chemotherapy. The 8-yr freedom from progression is around 40–55% and the overall survival around 70–55%, at present. Patients with disseminated disease (generally stages III and IV) are given six to eight cycles of CHOP (cyclophosphamide, hydroxydaunomycin, Oncovin® [vincristine], and prednisone) or a comparable regimen (seeTable 6).

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