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    X11,310 after they have reached maturity (Miller, buy viagra online in nz 1985). In the mouse, IL-3 is implicated in the further differentiation and maturation of cultured mast cells (Miyajima et al, 1987). Note large electron dense cytoplasmic granules which store the mast cell mediators. Mag. The extensive mast cell proliferation in response to helminth infection (see Chapter 8), occurring particularly in the parasitized intestine is also highly T-cell dependent since it buy viagra online in nz can be adoptively transferred with T cells, does not occur in the athymic or immunocompromized host and can be suppressed by drugs which suppress T-cell function (Figure 3.3a, b.

    IMMUNITY AND PATHOLOGY 33 Figure 5.4. Ultrastructure of a rat mucosal mast cell in situ in the jejunum. Mast-cell recruitment and differentiation in rodents is IL-3 dependent, but it is not yet certain whether IL-5 is responsible for mast cell growth in man because it has proved very difficult to grow human mast cells in vitro.

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    1988, marks et al.. Alkondon and Albuquerque, 1994. Li et al., 1994), and acute systemic administration of a high nicotine dose increased the release of serotonin in the frontal cortex of rats.

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