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    In contrast, the primary motor cortex has a thin layer IV and a thick layer V (Figure buy viagra in europe 2-17 ). Association areas of the cerebral cortex, such as prefrontal and parietal-temporal-occipital association cortex, have a morphology that is intermediate between those of sensory cortex and motor cortex. This is the layer in which axons from most thalamic sensory neurons synapse. As does the P.33 density of neurons in each layer, the thickness of the six principal cell layers varies.

    Layer V contains the neurons that project to the spinal cord, via the corticospinal tract. Areas that subserve sensation (eg, primary visual cortex) have a thick layer IV (Figure 2-16 ). Figure 3-8.

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    In vivo, DA neurons can also fire in buy viagra in europe a pacemaker mode, and this is thought to produce persistent release of relatively small amounts of DA (Overton & Clark, 1997). When spikes of DA neurons are clustered into bursts, the increase in extracellular DA in the projection areas is much greater than that observed for regularly spaced trains of action potential at the same average frequency, due to supralinear summation (Bean & Roth, 1989. Wightman & Zimmerman, 1989). Single-spike firing, often irregular, and burst firing (Grace & Bunney, 1985a, 1984b.

    Suaud-Chagny, Chergui, Chouvet, & buy viagra in europe Gonon, 1991). 2005, one possible explanation is that DA release outpaces DA uptake (Cragg & Rice. Tepper, Martin, & Anderson, 1996) (Figure 7.4). 1997, overton & Clark.

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