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Stereology-based estimates of synapse number buy generic levitra australia in the frontal cortex also suggested that the frontal cortex synapse number appears unaffected with age in nondemented individuals , a study using unbiased. Variable reports may stem from the cases included in the study, the region of frontal cortex examined, and other possible methodological issues (e.g., types of synapse number and quantification methods). Masliah, Mallory, buy generic levitra australia Hanson, DeTeresa, & Terry, 1989), but others show no change with age (Haas, Hung, & Selkoe, 1991. Honer, Dickson, Gleeson, & Davies, 1993). Liu and Brun , on the other hand, found a progressive, age-related loss of frontal cortical synapse density amounting to roughly 30% between ages 21 and 100.