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    This could vary throughout the human population and thereby result in interindividual variability in levels of expression of metabolitemodified liver neoantigens. Consequently, patients who express relatively high levels of neoantigens derived from volatile anesthetics are likely to be at greater risk of developing a neoantigen-driven immune response, and sustaining immune-mediated liver injury, than patients who express lower levels of the neoantigens.

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    In each case the performance measure or the computational model is related to a theory of brain function, however.

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