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  • RESEARCH 4 BUSINESS 2016, Ljubljana, 5 and 6 of May 2016

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  • A small group 3 viagra pills joke of children with adenosine-deaminase deficiency has been treated by gene transfer. The first children in which the ADA gene was transferred obtained about 25% of the normal ADA levels and had fewer infections than before. As a consequence of the deficient enzyme, adenosine and desoxy-adenosine triphosphate accumulate in cells, thus interfering with DNA synthesis.

    These patients have severely defective T- and B-cells (SCID). Clinical Gene Therapy Protocols Gene therapy is an attractive idea for hematological disorders, in which stem cells can be treated, and for cancer in general, in which patients have limited options after relapse. The first group of studies aims at the replacement of missing genes.

    T-cells from children with ADA deficiency were infected in vitro with ADA-expressing retroviruses, then re-infused into the children after in vitro culture. The administration of transfected lymphocytes has to be repeated every 3–7 mo.

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    The CT appearance is also varied. Which may calcify, serous tumors calcify more commonly than any other pancreatic tumors and are typified by a central stellate scar.

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